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Treatment Details

Doxylamine (FT Sleep Aid)

Brand Name: NA
Drug Class: 1st generation antihistamine
FDA Category: Over-the-Counter Medication
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Overview

DOXYLAMINE  What is doxylamine. In contrast with other antihistamines typically used for allergy symptoms, doxylamine is a first-generation antihistamine commonly used as a short-term treatment for insomnia. However, it can also be used for allergy symptoms such as nasal congestion, sneezing, runny nose, and itchy nose, as well as nausea and vomiting in pregnancy (when combined with pyridoxine or vitamin B6). For adults or children ages 12 and older, it can be taken as 25-50 mg at bedtime as needed for insomnia.   How can doxylamine help alleviate certain long COVID symptoms?  Sleep-related disturbances are common after COVID and may be present in up to 52% of long COVID patients.1 Insomnia can also contribute to downstream effects such as metabolic and cardiovascular diseases, immune responses, and increased depression and anxiety. While non-pharmacological measures for treating insomnia are preferred, such as maintaining good sleep habits, maximizing exposure to natural daylight, especially in the morning, and following a night routine, pharmacological measures such as doxylamine can improve sleep.

Relevant Studies

PMC9970199 – www.ncbi.nlm.nih.gov

Read Study →

Does Nyquil Make You Sleepy – www.sleepfoundation.org

Read Study →

19932820.2023.2182704 – www.tandfonline.com

Read Study →

How it works:

Blocks histamine type 1 receptors, blocks chemoreceptor trigger zone

Dosage Form: Tablet Tablet - 25mg

Common Usage: insomnia

Precautions:

Pregnancy

Studies in pregnant women have not demonstrated a risk to the fetus during the first trimester.

Lactation

Usually compatible with breastfeeding with small, occasional doses

Warnings

contraindications include hypersensitivity to drug or ingredients,

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 05:10AM

Last Update Date: Sep 14, 2024, 07:32PM