Overview

HYDROXY-BETA-METHYLBUTYRATE   What is hydroxy-beta-methylbutyrate. Hydroxy-beta-methylbutyrate, or HMB, is a substance made during the body’s breakdown of the amino acid leucine [[1]].   What does hydroxy-beta-methylbutyrate do in the body. HMB has many roles in the body. It is involved in forming proteins from amino acids, insulin activity, increase and growth of muscle cells, and stem cell growth and specialization into mature cells, among other functions [[2]].   HMB reduces muscle damage from exercise, strengthens muscle, improves aerobic performance, and heightens fatigue resistance.

How it works:

"HMB has many roles in the body. It is involved in forming proteins from amino acids; insulin activity; increase and growth of muscle cells; and stem cell growth and specialization into mature cells, among other functions. HMB reduces muscle damage resulting from exercise and strengthens muscle, improves aerobic performance, and heightens resistance to fatigue. In older people, HMB can reduce sarcopenia, or the loss of muscle and strength that occurs when people get older and exercise less. Optimal effects of HMB in the elderly occur with oral supplementation in conjunction with exercise. In older people who are frail, HMB supplementation helps reduce the decline of muscle mass and helps preserve muscle function, especially for those elderly patients who are in hospital stays. HMB may play a role in regulating the immune and inflammatory responses, especially under conditions of stress. HMB was found to exhibit anti-inflammatory effects, protect against muscle breakdown, and improve pulmonary function in patients in the intensive care unit for chronic obstructive pulmonary disease."

Dosage Form: Tablet N/A

Common Usage: Used to reduce muscle mass decline in elderly