Treatment Details
Maraviroc
Overview
MARAVIROC What is maraviroc (Selzentry). Maraviroc is a medication used to treat human immunodeficiency virus (HIV) in both children and adults. It works by binding to a receptor on HIV, prohibiting it from entering the cells [1]. Maraviroc is not a stand-alone treatment and must be used in combination with other HIV medications. How does the use of maraviroc relate to long-COVID. For patients with long-COVID, treatment options are limited and undefined.
Relevant Studies
Maraviroc – www.antimicrobe.org
PMC9944830 – www.ncbi.nlm.nih.gov
NCT04435522 – clinicaltrials.gov
How it works:
Selective antagonist between CCR5 and HIV-1 gp120
Dosage Form: Tablet Tablet - 150mg, 300mg , Oral solution - 20mg/mL
Common Usage: HIV-1 Infection
Precautions:
Pregnancy
Limited data on the use of maraviroc during pregnancy from the APR and case reports are not sufficient to inform a drug-associated risk of birth defects and miscarriage
Lactation
The Centers for Disease Control and Prevention recommend that HIV-1-infected mothers in the United States not breastfeed their infants to avoid risking postnatal transmission of HIV-1 infection
Warnings
Black Box Warning: Hepatotoxicity, systemic allergic reaction , Contraindicated: severe renal impairment or ESRD with concomitant CYP3A inducers or inhibitors , Warnings: Preexisting liver dysfunction, co-infection with Hepatitis B or C, cardiovascular events, hypersensitivity
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Submission Date: Apr 16, 2024, 07:09AM
Last Update Date: Sep 14, 2024, 06:43PM
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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.
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