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Treatment Details

Naproxen

Brand Name: NA
Drug Class: Nonsteroidal anti-inflammatory drug…
FDA Category: Over-the-Counter Medication
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Overview

NAPROXEN What is naproxen. Naproxen is a non-steroidal anti-inflammatory (NSAID) medication commonly used to relieve pain and reduce fevers. Unlike acetaminophen, naproxen has anti-inflammatory properties and can be used for inflammatory diseases such as osteoarthritis and rheumatoid disorders. It is typically taken as 500 mg followed by 250-500 mg every 12 hours as needed for the immediate-release formulation or 1 g once daily for the extended-release formulation.   How can naproxen help alleviate certain long COVID symptoms?  Naproxen works by reversibly inhibiting enzymes in our body called COX-1 and COX-2 that help reduce fever, pain, and inflammation. It is also believed to reduce pro-inflammatory substances called cytokines and inhibit the activation of other immune cells that can cause inflammation.

Relevant Studies

PMC9971680 – www.ncbi.nlm.nih.gov

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Head.13903 – headachejournal.onlinelibrary.wiley.com

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S41533 022 00300 Z – www.nature.com

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How it works:

Reversibly inhibits COX-1 and 2 enzymes

Dosage Form: Tablet Capsule - 220mg; Tablet - 250mg, 375mg, 500mg; Tablet (sodium) - 220mg, 275mg, 550mg; Delayed release tablet - 375mg, 500mg; Extended release tablet - 375mg, 500mg, 750mg; Suspension - 125mg/5mL

Common Usage: pain, fever, migraine, menstrual cramps, gout, osteoarthritis

Precautions:

Pregnancy

Birth defects have been observed. Can be continued during first 2 trimesters of pregnancy, but use is not recommended in third trimester.

Lactation

Usually compatible with breastfeeding. Other agents preferred

Warnings

contraindications include hypersensitivity to drug or ingredients, NSAID- induced asthma , NSAID Induced urticaria, advanced kidney disease

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 15, 2024, 01:07PM

Last Update Date: Sep 14, 2024, 07:43PM