Overview

OXYMETAZOLINE NASAL SPRAY What is oxymetazoline. Oxymetazoline (Afrin) is a decongestant that constricts the blood vessels in your nose to reduce nasal swelling and congestion. It can be applied by spraying 2-3 sprays in each nostril twice a day, with a maximum daily dose of 2 doses in a 24-hour period.   How can oxymetazoline help alleviate certain long COVID symptoms?  Oxymetazoline can be used for nasal congestion that persists after a COVID infection, but it should not be used long-term. Unlike oral decongestants like pseudoephedrine or phenylephrine, which can increase blood pressure in people with high blood pressure, oxymetazoline has fewer effects on blood pressure and can be more beneficial in these patients.   What evidence supports oxymetazoline’s use for long COVID.

How it works:

Stimulates alpha-adrenergic receptors in the nasal mucosa, resulting in vasoconstriction

Dosage Form: Tablet Nasal spray - 0.05% (15mL)

Common Usage: nasal congestion, post-nasal drip