Overview

SYSTEMIC PROTEOLYTIC ENZYMES    What are systemic proteolytic enzymes?                                                                                             We previously discussed bromelain’s utility in reducing inflammation. Bromelain, discussed in this guide, belongs to a larger class of systemic proteolytic enzymes, or SPEs. SPEs break down proteins to help facilitate normal body processes such as digestion or pain relief. They can also be used to reduce swelling and help with wound healing cleanup [[1]].   Other SPEs include lysozyme, catalase, and papain. SPEs break down proteins into smaller fragments and, ultimately, into amino acids, which are the building blocks of proteins and other vital molecules the body uses for various purposes [[2]].

How it works:

"SPEs can be taken as oral supplements or applied to the skin. Applied to the skin, they can aid in cleaning up tissue from wounds to support healthy wound healing. As a supplement, SPEs can work in the body to perform a variety of processes related to immune health, digestion, and more. Relevant to COVID-19 and its impact on the immune system in Long COVID, SPEs are known modulators of the immune system. SPEs work to combat oxidative stress and prevent cell and tissue damage."

Dosage Form: Tablet For Long COVID, orally, 3x per day, on empty stomach (https://isom.ca/article/an-orthomolecular-protocol-for-long-covid/)

Common Usage: "Topical: Cleaning up tissue from wounds to support healthy wound healing Oral: Support immune health, digestion, and more"