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Treatment Details

Fenofibrate

Brand Name: Lofibra, TriCor, Fenoglide,
Drug Class: Fabric acid derivative
FDA Category: Prescription Medication
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Overview

FENOFIBRATE   What is fenofibrate. Fenofibrate is part of a class of medications known as fibric acid derivates. Their primary function is to lower triglyceride levels and increase HDL cholesterol levels in patients.   How does fenofibrate work. Cholesterol in the body is made up of two parts: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL is often referred to as the “bad” cholesterol, as an abundance of this type can lead to heart attacks, stroke, and other health problems.

Relevant Studies

Art 20046388 – www.mayoclinic.org

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S00011 022 01615 W – link.springer.com

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Fenofibrate Covid – www.goodrx.com

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How it works:

Decreases liver uptake of free fatty acids, inhibits secretion of VLDL, inhibits peripheral lipolysis

Dosage Form: Tablet Tablet (TriCor) - 48mg, 145mg , Tablet (Lofibra) - 54mg, 160mg , Tablet (Fenoglide) - 40mg, 120mg , Tablet (Triglide) - 160mg , Capsule (Lipofen) - 50mg, 150mg

Common Usage: Lowering triglyceride levels

Precautions:

Pregnancy

In patients who are pregnant who develop severe hypertriglyceridemia and are at risk for pancreatitis, use of fenofibrate beginning in the second trimester is one intervention that may be considered

Lactation

Due to the potential for serious adverse reactions in the breastfed infant (such as disrupting lipid metabolism), breastfeeding is contraindicated by the manufacturer

Warnings

Contraindicated: Hypersensitivity, active liver disease, pre-existing gallbladder disease, severe kidney impairment, breastfeeding, persistent liver function abnormalities ; Warnings: Cholelithiasis, pancreatitis, venous thromboembolism (VTE), hematologic effects, paradoxical HDL decrease

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 07:55AM

Last Update Date: Sep 14, 2024, 06:21PM