Overview

Fexofenadine (Allegra):    What is fexofenadine?  Fexofenadine is an over-the-counter antihistamine medication used to relieve allergy symptoms such as watery eyes, an itchy nose, sneezing, and hives. It is considered to be the least sedating and preferred option for people to take during the day.   How can fexofenadine help with long COVID symptoms?   Histamine is a chemical our immune system releases that causes our allergy symptoms. Cells in our body called mast cells release histamine, and in some patients after COVID, they may release too much, leading to some of the symptoms of long COVID. Two types of drugs can block histamine in the body, which we call our H1- and H2-antihistamines. Blocking histamine can lead to anti-inflammatory effects that relieve certain long COVID symptoms.

How it works:

Blocks histamine type 1 receptors

Dosage Form: Tablet Tablet - 60mg, 180mg; ER tablet - 180mg; Oral disintegrating tablet (for children) - 30mg; Suspension (for children) - 30mg/5mL

Common Usage: allergy symptoms such as runny nose, itchy eyes/nose, sneezing, "hay fever", hives