Overview

MELATONIN   What is melatonin. Melatonin is a hormone produced by the brain’s pineal gland in darkness. Melatonin synthesis relies on the amino acid tryptophan [[1]].   What does melatonin do in the body. Melatonin helps regulate the sleep-wake cycle and helps us sleep. Light exposure at nighttime can block the production of melatonin [[2]].

How it works:

"Melatonin helps regulate the sleep-wake cycle and helps us sleep. Light exposure at nighttime can block the production of melatonin. While it is known as a sleep-promoting molecule, it also activates a molecule called NRF2, which plays an antioxidant role and prevents macrophages from acting in pro-inflammatory ways. At high doses, melatonin can be a robust scavenger of free radicals, a feat which it accomplishes through interacting with enzymes that boost the body’s antioxidant defenses. Relevant to SARS-CoV-2, the virus that causes COVID-19, researchers believe melatonin has a variety of helpful functions: impairing COVID-19 infection; anti-oxidant, anti-inflammatory, and immunoregulatory properties; restoring and maintaining a sleep-wake cycle (also known as the circadian rhythm); treating comorbidities of COVID-19 including metabolic syndrome, diabetes, and cardiovascular issues; neuroprotection; boosting function of COVID-19 vaccines."

Dosage Form: Tablet Oral - N/A

Common Usage: Sleep