Overview

PALMITOYLETHANOLAMIDE (PEA)   What is palmitoylethanolamide or PEA. Palmitoylethanolamide, also called PEA, is part of a fatty acid found in the body. The body makes PEA on demand [[1]]. Oddly enough, PEA can be found in legumes, peas, beans, vegetables, tomatoes, and potatoes. PEA is also found in milk, egg yolks, soy oil, and corn [[2]].   PEA is a cannabimimetic compound, which means that it affects the endocannabinoid system.

How it works:

"PEA is synthesized on demand by the body. It works to balance cell and tissue processes that are needed to maintain health of the nervous system and reduce neuroinflammation. PEA has anti-inflammatory, immune modulating, neuroprotective, and pain-relieving properties. It performs a variety of functions, including combatting chronic pain and inflammation. Because it has a protective response that occurs in response to cellular injury, levels of PEA are often higher in disease states. PEA acts on cannabinoid receptors and inhibits the breakdown of the endocannabinoid anandamide, boosting its activity, via the “entourage effect.”"

Dosage Form: Tablet Oral: 600 mg, 2x per day (https://isom.ca/article/an-orthomolecular-protocol-for-long-covid/)

Common Usage: To counteract chronic pain and inflammation