Palmitoylethanolamide

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Side Effects

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10 Relevant Research Studies

Most-Reviewed Use: ANTIBIOTICS

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Brand Name: NA

Drug Class: Supplement

FDA Category: supplement

CompendiRx Topic(s): Brain and Nerves, Joint and Muscles

Dosage Form: Tablet Oral: 600 mg, 2x per day (https://isom.ca/article/an-orthomolecular-protocol-for-long-covid/)

Common Usage: To counteract chronic pain and inflammation

How it works

"PEA is synthesized on demand by the body. It works to balance cell and tissue processes that are needed to maintain health of the nervous system and reduce neuroinflammation. PEA has anti-inflammatory, immune modulating, neuroprotective, and pain-relieving properties. It performs a variety of functions, including combatting chronic pain and inflammation. Because it has a protective response that occurs in response to cellular injury, levels of PEA are often higher in disease states. PEA acts on cannabinoid receptors and inhibits the breakdown of the endocannabinoid anandamide, boosting its activity, via the “entourage effect.”"

Pregnancy

No data exists about the safety of PEA for pregnancy or breastfeeding. Therefore, it is best to avoid PEA during pregnancy and breastfeeding.

Lactation

No data exists about the safety of PEA for pregnancy or breastfeeding. Therefore, it is best to avoid PEA during pregnancy and breastfeeding.

Warnings

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