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Treatment Details

Paroxetine

Brand Name: Paxil, Brisdelle, Pexeva
Drug Class: Antidepressant (SSRI)
FDA Category: Prescription Medication
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Overview

Paroxetine (Paxil)     What is paroxetine (Paxil). Most used for anxiety and depression, paroxetine belongs to a class of medication called selective serotonin reuptake inhibitors (SSRIs). Serotonin is a molecule in the body that aids in mood, sexual desire, sleep, digestion, wound healing, bone health, and blood clotting [1]. It is often referred to in psychology as the “happy” chemical. In conditions like depression and anxiety, the brain is dealing with an imbalance of chemicals such as serotonin. SSRIs, like paroxetine, work by keeping serotonin in the space where it can readily be available for bodily processes.      What is the connection between paroxetine and long-COVID.

Relevant Studies

Long COVID 19 Clinical Guidelines English April 21 2021 – www.ohsu.edu

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Search – clinicaltrials.gov

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22572 Serotonin – my.clevelandclinic.org

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How it works:

Blocks the reuptake of serotonin

Dosage Form: Tablet Tablet - 10mg, 20mg, 30mg, 40mg ; Capsule - 7.5mg ; Tablet (XR) - 12.5mg, 25mg, 37.5mg ; Oral suspension 10mg/5mL

Common Usage: Depression, obsessive compulsive disorder (OCD), social phobia, anxiety, posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), menopausal vasomotor symptoms

Precautions:

Pregnancy

Consideration should be given to switching to other treatment options, including another antidepressant or non-pharmaceutical treatment such as cognitive behavioral therapy. Treatment with paroxetine should only be continued for an individual patient, if the potential benefits outweigh the potential risks

Lactation

Lactating women should not nurse their infants while receiving paroxetine unless in the opinion of the treating health professional, breast feeding is necessary, in which case the infant should be closely monitored

Warnings

Black Box Warning: Increased risk of suicidal thoughts in children and adolescents. Closely monitor for clinical worsening or emergency of suicidal thoughts or behaviors ; Contraindicated: concomitant use of MAOI, concomitant use of pimozide, hypersensitivity ; Warnings: serotonin syndrome, increased risk of bleeding with NSAIDS, seizures, angle closure glaucoma, activation of mania/hypomania

© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 08:08AM

Last Update Date: Sep 14, 2024, 06:38PM