Azithromycin

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3 Relevant Research Studies

Most-Reviewed Use: ANTIBIOTICS

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Brand Name: Zithromax

Drug Class: Antibiotic (Macrolide)

FDA Category: Prescription Medication

CompendiRx Topic(s): Antivirals and Antibiotics

Dosage Form: Tablet Tablet - 250mg, 500mg ; Oral suspension - 100mg/5mL, 200mg/5mL ; Injection (powder for reconstitution) - 500mg/ vial ; opthalmic suspension -

Common Usage: Community-acquired pneumonia, pharyngitis, tonsillitis, COPD exacerbation, pelvic inflammatory disease (PID), genital ulcer disease, acute bacterial sinusitis, uncomplicated skin structure, urethritis, Cervicitis

How it works

Binds to 50S ribosomal unit causing disruption of protein synthesis of bacteria

Pregnancy

Currently, there is no conclusive evidence to support that azithromycin use by pregnant women causes adverse outcomes in their offspring. Therefore, this agent should only be used during pregnancy when clinically indicated, if the benefits of treatment are expected to outweigh the potential risks

Lactation

There are no available data on the effects of azithromycin on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for azithromycin and any potential adverse effects on the breastfed infant from azithromycin or from the underlying maternal condition

Warnings

"Contraindications: Hypersensitivity, cholestatic jaundice/hepatic dysfunction associated with use of azithromycin ; Warnings: Serious allergic reactions, Infantile Hypertrophic Pyloric Stenosis (IHPS), hepatotoxicity, Clostridioides difficile-Associated Diarrhea, QT prolongation, muscle weakness exacerbation in patients with myasthenia gravis"

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Azithromycin

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