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Treatment Details

Azithromycin

Brand Name: Zithromax
Drug Class: Antibiotic (Macrolide)
FDA Category: Prescription Medication
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Overview

AZITHROMYCIN   What is azithromycin (Zithromax). Azithromycin is an antibiotic used to treat bacterial infections such as pneumonia, sinusitis, and sexually transmitted diseases. It works by preventing bacteria from making proteins. Without proteins, bacteria cannot survive and die. Azithromycin is commonly prescribed in the outpatient setting under the name “Z-pack.”   Can azithromycin help with long-COVID. At the beginning of the COVID-19 pandemic, azithromycin had gained some headway as a potential treatment option for COVID-19 due to its antiviral properties and modifying effects on the immune system.

Relevant Studies

E000806 – bmjopenrespres.bmj.com

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PMC9404997 – www.ncbi.nlm.nih.gov

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Amr 5 022 – scholars.direct

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How it works:

Binds to 50S ribosomal unit causing disruption of protein synthesis of bacteria

Dosage Form: Tablet Tablet - 250mg, 500mg ; Oral suspension - 100mg/5mL, 200mg/5mL ; Injection (powder for reconstitution) - 500mg/ vial ; opthalmic suspension -

Common Usage: Community-acquired pneumonia, pharyngitis, tonsillitis, COPD exacerbation, pelvic inflammatory disease (PID), genital ulcer disease, acute bacterial sinusitis, uncomplicated skin structure, urethritis, Cervicitis

Precautions:

Pregnancy

Currently, there is no conclusive evidence to support that azithromycin use by pregnant women causes adverse outcomes in their offspring. Therefore, this agent should only be used during pregnancy when clinically indicated, if the benefits of treatment are expected to outweigh the potential risks

Lactation

There are no available data on the effects of azithromycin on milk production. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for azithromycin and any potential adverse effects on the breastfed infant from azithromycin or from the underlying maternal condition

Warnings

"Contraindications: Hypersensitivity, cholestatic jaundice/hepatic dysfunction associated with use of azithromycin ; Warnings: Serious allergic reactions, Infantile Hypertrophic Pyloric Stenosis (IHPS), hepatotoxicity, Clostridioides difficile-Associated Diarrhea, QT prolongation, muscle weakness exacerbation in patients with myasthenia gravis"

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 08:10AM

Last Update Date: Sep 14, 2024, 07:22PM