Treatment Details
Simvastatin
0
Effectiveness
0
Side Effects
0
Cost
4
Relevant Research Studies
Most-Reviewed Use: ANTIBIOTICS
Ratings
0 Comments
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Brand Name: Zocor
Drug Class: Statin (HMG-CoA reductase inhibitor)
FDA Category: Prescription Medication
CompendiRx Topic(s): Metabolism and Hormones
Dosage Form: Tablet Tablet - 5mg, 10mg, 20mg, 40mg , Oral solution - 4mg/mL, 8mg/mL
Common Usage: Lowering cholesterol, Prevention of cardiovascular events
How it works
Inhibits HMG-CoA reductase during cholesterol synthesis in the liver
Pregnancy
Simvastatin may cause fetal harm when administered to pregnant patients based on the mechanism of action. Discontinue simvastatin when pregnancy is recognized. Alternatively, consider the ongoing therapeutic needs of the individual patient
Lactation
Because of the potential for serious adverse reactions in a breastfed infant, based on the mechanism of action, advise patients that breastfeeding is not recommended during treatment with simvastatin
Warnings
"Contraindicated: Hypersensitivity to simvastatin, active liver disease or unexplained transaminase elevations, pregnancy, lactation Warnings: Strong CYP3A4 inhibitors, myopathy, rhabdomyolysis, liver enzyme abnormalities"
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Submission Date: Apr 16, 2024, 07:21AM
Last Update Date: Jul 27, 2024, 08:12PM
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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.
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