Umeclidinium/Vilanterol

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Brand Name: Anoro, Ellipta

Drug Class: LAMA/LABA combo

FDA Category: Prescription Medication

CompendiRx Topic(s): Lungs

Dosage Form: Tablet Powder for inhalation - 62.5mcg/25mcg

Common Usage: Chronic obstructive pulmonary disease (COPD)

How it works

Blocks acetylcholine at the M1-M5 receptors/ Long acting selective beta-2 adrenergic agonist

Pregnancy

There are insufficient data on the use of umeclidinium/vilanterol in pregnant women to inform a drug-associated risk

Lactation

The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for umeclidinium/vilanterol and any potential adverse effects on the breastfed child from umeclidinium or vilanterol or from the underlying maternal condition

Warnings

Contraindicated: Severe hypersensitivity to milk proteins, use of LABA without an inhaled corticosteroid is contraindicated in those with asthma ; Warnings: Do not use for acute treatment or in deteriorating COPD, caution in those with cardiovascular disorders, caution in thyrotoxicosis, seizure disorders, diabetes mellitus and ketoacidosis, watch for narrow-angle glaucoma, urinary retention, watch for hypokalemia and hyperglycemia

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