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Treatment Details

Bupropion

Brand Name: Aplenzin, Budeprion, Buproban,
Drug Class: Atypical antidepressant (NDRI)
FDA Category: Prescription Medication
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Overview

BUPROPION   What is bupropion. Bupropion is a medication that is commonly used to treat depression, seasonal affective disorder (SAD), and smoking cessation. It is an atypical antidepressant in that it is not in the selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) class. Bupropion works by inhibiting the reuptake of norepinephrine and dopamine in the brain. These chemicals are used in reward- and emotion-related behavior [1]. In depression, there is an imbalance of these chemicals in the brain.

Relevant Studies

Acschemneuro.7b00056 – pubs.acs.org

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Long Covid Is There A Role For Antidepressants 1249 – www.medtextpublications.com

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How it works:

Unknown, may act through dopaminergic or noradrenergic pathways

Dosage Form: Tablet Tablet - 75mg, 100mg, Tablet (SR) - 100mg, 150mg, 200mg , Tablet (Wellbutrin XL) - 150mg, 300mg , Tablet (Aplenzin) - 174mg, 348mg, 522mg , Tablet (Forfivo XL) - 450mg

Common Usage: Major depressive disorder, seasonal affective disorder, smoking cessation

Precautions:

Pregnancy

If treatment for major depressive disorder is initiated for the first time during pregnancy, agents other than bupropion are preferred

Lactation

When first initiating an antidepressant in a patient who is breastfeeding, agents other than bupropion are preferred; however, maternal use of bupropion is not considered a reason to discontinue breastfeeding. According to the manufacturer, the decision to breastfeed during therapy should consider the risk of infant exposure, the benefits of breastfeeding to the infant, and benefits of treatment to the mother

Warnings

"Black Box Warning: Suicidal thoughts and behaviors in children and adolescents ; Contraindicated: Hypersensitivity, anorexia/bulimia, concomitant use with MAOIs, seizure disorder Warnings: Hepatotoxicity, hepatic cirrhosis, sexual dysfunction, mydriasis,"

© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 07:48AM

Last Update Date: Sep 14, 2024, 06:17PM