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Treatment Details

Methylene -Blue

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6 Relevant Research Studies

Most-Reviewed Use: ANTIBIOTICS

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Brand Name: ProvayBlue

Drug Class: Antidote; Phenothiazine Derivative

FDA Category: supplement

CompendiRx Topic(s): Brain and Nerves

Dosage Form: Tablet Oral or IV, depending on the exact use (UpToDate lists many different doses based on different conditions).

Common Usage: It can improve the body’s ability to take up oxygen and improve liver function; it can also improve blood pressure and cardiac function in septic shock.

How it works

Though methylene blue started out as a textile dye, it has also been in use for over a century as a medicinal compound. Methylene blue is low-cost and safe at low dosages. Used to treat COVID-19, methylene blue can interact with the virus itself, blocking the viral replication process. Methylene in methylene blue can also interfere with pro-inflammatory cells and prevent the cytokine storm, which results from immune overreactivity, in the lungs. Methylene blue is also a nitric oxide synthase inhibitor, which means it slows COVID-19 disease progression and increases oxygen saturation, which improves COVID-19 outcomes.

Pregnancy

Methylene blue is not safe for pregnancy or breastfeeding. It can be harmful to a developing fetus and should be avoided in pregnancy and during breastfeeding.

Lactation

Methylene blue is not safe for pregnancy or breastfeeding. It can be harmful to a developing fetus and should be avoided in pregnancy and during breastfeeding.

Warnings

From UpToDate: "Methylene blue may cause serious or fatal serotonergic syndrome when used in combination with serotonergic drugs and opioids. Avoid concomitant use of methylene blue with selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), monoamine oxidase inhibitors, and opioids."

© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 12:35PM

Last Update Date: Jul 27, 2024, 05:32PM