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Treatment Details

Zafirlukast

Brand Name: Accolate
Drug Class: Leukotriene receptor antagonist
FDA Category: Prescription Medication
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Overview

ZAFIRLUKAST   What is Zafirlukast (Accolate). Zafirlukast is part of a class of medications known as leukotriene receptor antagonists. Leukotrienes, specifically LTC4, LTD4, and LTE4, are pro-inflammatory mediators heavily involved in the mechanisms behind asthma. When provoked, leukotrienes constrict the airways, making breathing harder. Zafirlukast blocks leukotrienes from closing the airways, effectively making breathing easier.    What is the relationship between Zafirlukast and long-COVID. For patients suffering from inflammatory respiratory symptoms of long-COVID such as wheezing, cough, exercise intolerance, and trouble breathing, zafirlukast may play a role in mitigating these symptoms [1].

Relevant Studies

Full – www.frontiersin.org

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PMC9673052 – www.ncbi.nlm.nih.gov

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How it works:

Competitive leukotriene receptor antagonist

Dosage Form: Tablet Tablet - 10mg, 20mg

Common Usage: Asthma

Precautions:

Pregnancy

Agents other than zafirlukast are preferred for the treatment of asthma in pregnancy. Outcome data following maternal use of zafirlukast in pregnancy are limited

Lactation

Due to the potential for adverse reactions in the breastfeeding infant, breastfeeding is not recommended by the manufacturer.

Warnings

Contraindicated: Hypersensitivity, hepatic impairment ; Warnings: Eosinophilia, hepatotoxicity, neuropsychiatric events, increased risk of infection

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 07:31AM

Last Update Date: Sep 14, 2024, 07:08PM