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Treatment Details

Metformin

Brand Name: Fortamet, Glucophage, Glumetza,
Drug Class: Anti-diabetic (biguanide)
FDA Category: Prescription Medication
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Overview

METFORMIN   What is metformin. Metformin is a first-line agent used in the treatment of Type II diabetes. It helps lower blood sugar by decreasing the amount of blood sugar made in the liver and decreasing the amount of blood sugar absorbed by the gastrointestinal tract.   How can metformin impact long-COVID. Although used for diabetes, there has been some research conducted to look at its effects on those with long-COVID. A recent long-COVID study showed that 6.2% of patients using metformin received a long-COVID diagnosis compared to 10.3% of patients not using metformin [1].

Relevant Studies

Can Diabetes Treatment Reduce Risk Long Covid – covid19.nih.gov

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Metformin – www.covid19treatmentguidelines.nih.gov

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Search – clinicaltrials.gov

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How it works:

Decreases hepatic glucose production, decreases GI glucose absorption

Dosage Form: Tablet Tablet (IR) - 500mg, 850mg, 1000mg , Tablet (ER) - 500mg, 750mg, 1000mg , Oral solution - 100mg/mL , Oral suspension (ER) - 500mg/5mL

Common Usage: Type II diabetes mellitus

Precautions:

Pregnancy

Agents other than metformin are currently recommended to treat diabetes mellitus in during pregnancy (ADA 2022). Metformin may be considered for the treatment of gestational diabetes mellitus in patients who cannot safely or effectively use insulin

Lactation

According to the manufacturer, the decision to breastfeed during therapy should consider the risk of infant exposure, the benefits of breastfeeding to the infant, and the benefits of treatment to the mother.

Warnings

"Black Box Warning: Lactic acidosis ; Contraindicated: Hypersensitivity Warnings: Renal impairment, hepatic impairment, bariatric surgery, stress-related events,"

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 07:22AM

Last Update Date: Sep 14, 2024, 06:43PM