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Treatment Details

Indomethacin

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4 Relevant Research Studies

Most-Reviewed Use: ANTIBIOTICS

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Brand Name: Indocin, Tivorbex

Drug Class: Non-steroidal anti-inflammatory drug (NSAID)

FDA Category: Prescription Medication

CompendiRx Topic(s): Joint and Muscles

Dosage Form: Tablet Capsule - 20mg, 25mg, 40mg, 50mg , Capsule (ER) - 75mg , Powder for injection - 1mg , Oral suspension - 25mg/5mL , Suppository - 50mg

Common Usage: Acute pain relief, gout treatment, osteoarthritis

How it works

Inhibits COX-1 and COX-2 to inhibit synthesis of prostaglandins

Pregnancy

Maternal use of NSAIDs should be avoided beginning at 20 weeks' gestation. If NSAID use is necessary between 20 and 30 weeks' gestation, limit use to the lowest effective dose and shortest duration possible

Lactation

The manufacturer recommends that the decision to breastfeed during therapy consider the risk of infant exposure, the benefits of breastfeeding to the infant, and benefits of treatment to the mother. Maternal use of NSAIDs should be avoided if the breastfeeding infant has platelet dysfunction, thrombocytopenia, or a ductal-dependent cardiac lesion

Warnings

Black Box Warning: GI bleeds, serious cardiovascular thrombotic events ; Contraindicated: Hypersensitivity, use in setting of CABG surgery, history of proctitis or recent rectal bleeding ; Warnings: Hyperkalemia, kidney effects, corneal deposits, retinal disturbances, skin reactions, liver enzyme elevations

© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

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© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.

Submission Date: Apr 16, 2024, 07:42AM

Last Update Date: Jul 27, 2024, 09:43PM