Indomethacin
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Effectiveness
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Side Effects
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Cost
4 Relevant Research Studies
Most-Reviewed Use: ANTIBIOTICS
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Brand Name: Indocin, Tivorbex
Drug Class: Non-steroidal anti-inflammatory drug (NSAID)
FDA Category: Prescription Medication
CompendiRx Topic(s): Joint and Muscles
Dosage Form: Tablet Capsule - 20mg, 25mg, 40mg, 50mg , Capsule (ER) - 75mg , Powder for injection - 1mg , Oral suspension - 25mg/5mL , Suppository - 50mg
Common Usage: Acute pain relief, gout treatment, osteoarthritis
How it works
Inhibits COX-1 and COX-2 to inhibit synthesis of prostaglandins
Pregnancy
Maternal use of NSAIDs should be avoided beginning at 20 weeks' gestation. If NSAID use is necessary between 20 and 30 weeks' gestation, limit use to the lowest effective dose and shortest duration possible
Lactation
The manufacturer recommends that the decision to breastfeed during therapy consider the risk of infant exposure, the benefits of breastfeeding to the infant, and benefits of treatment to the mother. Maternal use of NSAIDs should be avoided if the breastfeeding infant has platelet dysfunction, thrombocytopenia, or a ductal-dependent cardiac lesion
Warnings
Black Box Warning: GI bleeds, serious cardiovascular thrombotic events ; Contraindicated: Hypersensitivity, use in setting of CABG surgery, history of proctitis or recent rectal bleeding ; Warnings: Hyperkalemia, kidney effects, corneal deposits, retinal disturbances, skin reactions, liver enzyme elevations
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Submission Date: Apr 16, 2024, 07:42AM
Last Update Date: Jul 27, 2024, 09:43PM
© 2024 CompendiRx.com. All Rights Reserved. Information on Ratings and Reviews is reported by our members and is not medical advice.
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